Search results for "pulse EPIR spectroscopy"

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Can copper(II) mediate Hoogsteen base-pairing in a left-handed DNA duplex? A pulse EPR study

2010

Pulse EPR spectroscopy is sued to investigate possible structural features of the copper(II) ion coordinated to poly(dG-dC) poly(dG-dC) in a frozen aqueous solution, and the structural change of the polynucleotide induced by the presence of the metal ion. Two different copper species were identified and their geometry explained by a molecular model. According to this model, one species is exclusively coordinated to a single guanine with the N7 nitrogen atom forming a coordinative bond with the copper. In the other species, a guanine and a cytosine form a ternary complex together with the copper ion. A copper crosslink between the N7 of guanine and N3 of cytosine is proposed as the most prob…

10120 Department of ChemistryCircular dichroismGuanineStereochemistryHoogsteen base pairrame strutture del DNA basi nucleotidiche EPR a impulsi risonanza paramagneticachemistry.chemical_elementTriple-stranded DNA3107 Atomic and Molecular Physics and OpticsNucleobasechemistry.chemical_compoundPolydeoxyribonucleotidesDNA structures540 ChemistryDNA Z-FormPhysical and Theoretical ChemistryBase PairingTernary complexCircular Dichroismstructure elucidationElectron Spin Resonance Spectroscopypulse EPIR spectroscopynucleobasesCopperSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Atomic and Molecular Physics and Opticschemistrycopper1606 Physical and Theoretical ChemistryCytosine
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